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One retrospective study of intra-articular knee injections reported symptomatic improvement lasting over six months following a single injection in 7 of 12 patients, suggesting potential for sustained effects beyond active treatment periods

This massive increase was seen after adjusting for age and body weight, so it cant be explained by an increase in longevity or obesity rates

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Clinical trials have utilized doses ranging from 1 mg per day up to 30 mg per day in divided doses for various administration routes, demonstrating safety across a wide dose spectrum

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Some people simply meet their weight-loss goal on GLP-1s and decide they dont want to continue, he says