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Once inside the cell, cytoplasmic thioesterases recognize the thioester bond and cleave the acetyl group, regenerating free reduced GSH directly in the cytoplasm

In the treated group, during the supplementation period, there was an increase in the levels of red blood cells and plasma reduced glutathione, hematocrit and hemoglobin and a concomitant decrease in plasma oxidized glutathione and reticulocytes with a maximum effect on the 120th day of therapy

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