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D., Gordish-Dressman, H., Hoffman, E

From molecular to nanotechnology strategies for delivery of neurotrophins: Emphasis on brain-derived neurotrophic factor (BDNF)

Never use plain sterile water or tap water for reconstitution, as they lack the preservatives needed for multi-dose vials

Collagen fibril diameter distribution of sheep anterior cruciate ligament

Solvent : For reconstitution, use a slightly acidic buffer (pH ~4-5) to slow deamidation

But the preclinical data, combined with growing clinical observations, suggests these compounds may support disc healing through mechanisms that conventional treatments simply do not address