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GLP-1 medications cause sulfur burps and bloating by slowing gastric emptying , which keeps food in the stomach longer and increases pressure and post-meal discomfort, especially after larger or higher-fat meals. Scientific explanation delayed gastric emptying and pyloric tone GLP-1 receptor agonists reduce gastric motility and increase pyloric sphincter tone , delaying the passage of solid food from the stomach into the small intestine
Fluid Balance : It might not sound glamorous, but proper fluid regulation is crucial for everything from kidney function to preventing dehydration
New England Journal of Medicine 376 , 17131722 (2017)
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GLP-1 contraindications These medications are not recommended if you have: Family history of medullary thyroid cancer Multiple endocrine neoplasia syndrome Gastroparesis Pancreatitis Kidney disease Poor kidney function Pregnancy Breastfeeding Type 1 diabetes Diabetic ketoacoidosis Previous or current eating disorder Cost of GLP-1 treatments Cost is considered one of the biggest downsides of GLP-1 therapy
J.RosenstockJ.Prez ManghiF
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