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Some research suggests that hyperhomocysteinaemia may contribute to endothelial dysfunction and low-grade systemic inflammation, though a direct link to joint pain remains unproven

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Break periods between cycles Between AOD-9604 cycles, a break period allows receptor sensitivity to restore and prevents potential adaptation that could reduce effectiveness in future cycles

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Tirzepatide: Another Relevant Comparison Tirzepatide (Mounjaro/Zepbound), a dual GIP/GLP-1 agonist approved by the FDA, provides another useful reference point