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Sialic acid exacerbates gut dysbiosis-associated mastitis through the microbiota-gut-mammary axis by fueling gut microbiota disruption

To our surprise, Rag2 / H4R / mice exhibited more profound weight loss and lower survival rates compared with Rag2 / mice (Figure 7a,b)

European Journal of Nutrition , 54(2), 251-263

Hedgehog pathway inhibitors such as vismodegib and IPI-926 have shown only modest responses in clinical trials for solid tumors, in part owing to acquired resistance mechanisms such as SMO mutations that sustain downstream signaling despite pharmacologic blockade

Estrogen receptors and signaling in fibroids: role in pathobiology and therapeutic implications

The GHIGF-1 axis The axis runs from the hypothalamus to peripheral tissue in a cascade