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Glucose homeostasis abnormalities can lead to chronic hyperglycemia, causing oxidative stress

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These include proton pump inhibitors and H2 blockers, which are used to treat acid reflux or heartburn, and metformin, a diabetes medication

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Similarly, BACE1 expression in the hippocampus and cortex of APP/PS1 mice treated with ITP-LNP/siBACE1 was inhibited and similar to that in WT (saline control) mice compared with that in the other groups (Fig

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