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Part of the challenge is that the cost of the prescriptions, which is often not covered by insurance, pushes people to seek less expensive alternatives

Accessed 16 Aug 2025 Mollan SP, Mitchell JL, Ottridge RS et al (2021) Effectiveness of bariatric surgery vs community weight management intervention for the treatment of idiopathic intracranial hypertension

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Common Medications that Contribute to Weight Gain or Loss Orlistat, a reversible inhibitor of gastrointestinal lipase, is a common first choice for therapy because of its long history and lack of systemic effects due to limited absorption

10.1038/35012069 205 NakayaY.KanekoT.ShigemotoR.NakanishiS.MizunoN