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doi:10.1007/s10072-016-2757-9 Mantle D, Heaton RA, Hargreaves IP

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THF and its derivatives carry single-carbon units used in the production of DNA bases (purines and thymidylate) and in amino acid metabolism

The resulting reaction products absorbance was assessed colorimetrically at a wavelength of 355 nm

27 Inflammation Obesity associated with overnutrition induces macrophage infiltration and chronic hypoxia, causing low-grade inflammation in the adipose tissue 28 and the release of proinflammatory factors such as interleukin (IL)-1 and tumor necrosis factor (TNF-), 29,30 thus impairing insulin signaling pathway in a number of ways