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Chemistry 24 , 22772285 (2018)

OMahonySClarkeGBorreYDinanTCryanJ

Ottawa (ON): Canadian Pharmacists Association

The GSH/GSSG ratio of GSH, as well as other active redox couples, including NADP/NADPH and FAD/ FADH2, regulates and maintains cellular redox status

It has been demonstrated that increasing ROS could easily result in dysfunctions of proliferation or differentiation in AML, and could be an effective strategy for overcoming drug resistance in leukemia [21]

Aronne, Louis J et al