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It should also be noted that there was a protocol deviation in the renal impairment study whereby participants were assigned to renal function groups using an eGFR value expressed in mL/min/1.73 m 2 instead of mL/min

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Firstly, CD206 was employed as the M2 macrophage marker to confirm macrophage polarization status using immunofluorescence staining performed under inflammatory stimuli (LPS and IFN-)

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doi: 10.1002/hep.20023 57