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Samples of small volume (150-200L) were thawed under strict cooling conditions (+0C to +2C) within 12-15 minutes in an ice-water bath preferentially without agitation
A significant share of this growth is expected to come from outsourced biomanufacturing capacity additions by CDMOs/CMOs, which increasingly rely on robust, pre-validated chromatography platforms
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The S protein produced by these vaccines binds to ACE2, leading to its downregulation, which has been found to induce the release the IL-1 and IL-6 (97)
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