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Shea BT, Hammer RE, Brinster RL: Growth allometry of the organs in giant transgenic mice
In addition, we included semaglutide prescriptions where the brand was unknown, if the patient had prior evidence of obesity and no prior evidence of type 2 diabetes (T2D)
Similarly, people's bodies can adjust to GLP-1 doses, meaning the drug becomes less effective over time and the dose must be nudged to produce the desired amount of "hunger noise" reduction
doi: 10.1146/annurev.pharmtox.010909.105812 30 ChenYZhangX