Lifestyle changes (diet, exercise, sleep) improve weight maintenance, but do not fully prevent regain in most patients
Results vary based on: Starting weight Metabolic factors Consistency with treatment Most are mild and temporary: Nausea (usually subsides in weeks) Constipation Headaches Severe side effects are rare but include pancreatitis or gallbladder issues
It is also approved for people with a BMI of 27 kg/m2 or higher who have at least one weight-related comorbidity, such as type 2 diabetes, hypertension, or dyslipidemia
Some people may experience weight gain while taking Wellbutrin, although this is generally less common
As nephrologists assume a more active role in prescribing these medications, questions regarding their optimal integration into CKD treatment algorithms have become increasingly relevant
Focusing on high-protein intake and resistance training (weight lifting) is particularly important while taking these drugs to ensure that the weight you lose is fat, not muscle mass