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Acknowledgements We thank the Research and Extension Sector, Faculdade de Cincias Mdicas de Minas Gerais
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HPLC-Based measurement of cortical rotenone levels in the neonatal animals Rotenone (Rot) was measured from the complete cortices of neonatal animals treated with Rot, following the protocol described in 31
Some amino acids possess antioxidant properties that could theoretically protect against oxidative stress, which contributes to endothelial dysfunction and impaired NO bioavailability
This review systematically describes the multi-target mechanisms of SIRT1 in MASLD pathogenesis through its regulation of critical factors, including peroxisome proliferator-activated receptor gamma coactivator 1-, Forkhead Box O, and nuclear factor kappa-light-chain-enhancer of activated B cells, which govern hepatocyte lipid remodeling, mitochondrial quality control, autophagyendoplasmic reticulum stress balance, and Kupffer cell/T cell polarization