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Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception, for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation

Proposed mechanism of action: LDN, as referenced by naltrexone doses between 1 mg and 5 mg daily, binds non-selectively to all opioid receptors antagonistically but extremely transiently

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Because GLP-1 users are not one group

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That's roughly 7.6 million fewer adults classified as obese