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The compound is not scheduled under the Controlled Substances Act and is not explicitly banned but it also lacks FDA approval and has no place on the 503A Bulk Drug Substances List, which is the only pathway for licensed compounding pharmacies to legally dispense it

The same study showed that LC supplementation in humans was associated with decreased ACE2

Theres limited scientific evidence directly linking semaglutide use to vitamin B12 deficiency or recommending routine vitamin B12 supplementation for people taking semaglutide

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Zhang Q, Liu C, Shi R, Zhou S, Shan H, Deng L, Chen T, Guo Y, Zhang Z, Yang GY, Wang Y, Tang Y (2022) Blocking C3d(+)/GFAP(+) A1 astrocyte conversion with semaglutide attenuates blood-brain barrier disruption in mice after ischemic stroke

5th ed Oxford University Press (2015)