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The only evidence is experimental: your research outcomes stop aligning with published data, or dose-response curves flatten unexpectedly

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this suggests that adenosine may act as a homeostatic regulator of sleep, with higher levels promoting the need for rest (Huang et al., 2014)

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The dose may be increased to 2 tablets per day, as advised by a healthcare professional

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doi: 10.1016/j.molmed.2025.08.009

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Glutathione synthesis

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