doi:10.1016/j.rbmo.2020.08.013
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Co-targeting CDK2 and CDK4/6 overcomes resistance to aromatase and CDK4/6 inhibitors in ER+ breast cancer
Diet, sleep, and nutrient cofactors (C, B-complex, selenium) influence glutathione status
It is noteworthy that NIN could prevent nonalcoholic steatohepatitis by modulating the host metabolome and intestinal microbiome in MCD diet-fed mice ( 2.5.2.3 Effects of NIN on liver fibrosis A previous study has demonstrated that NIN ameliorated liver injury and liver fibrosis, decreased collagen deposition and cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) expression, and inhibited in flammation in CCl4-treated mice, which indicating that interrupting the cGAS-stimulator of interferon genes pathway contributed to reverse the fibrosis process (Hernndez-Aquino et al., 2019)
[DOI] [PubMed] [Google Scholar] 38.Aguil A, Tauler P, Sureda A, Cases N, Tur J, Pons A