In December 2025, Eli Lilly announced topline results from the phase-3 TRIUMPH-4 clinical trial evaluating the safety and efficacy of retatrutide in adults with obesity or overweight and knee osteoarthritis, and without diabetes, as an adjunct to healthy diet and physical activity
The study also evaluated improvements in knee osteoarthritis symptoms
Topical oxidized glutathione offers a targeted approach, allowing you to apply glutathione directly to areas of uneven skin tone or pigmentation
The Role of Cancer Pre-Screening Scientific Rationale for Oncological Screening The proangiogenic properties of BPC-157 and TB-500 raise notable concerns regarding their use in individuals who may harbor subclinical or undiagnosed malignancies
STEP stands for Semaglutide Treatment Effect in People with Obesity and is an ongoing program initiated by Novo Nordisk that consists of several studies (STEP 1-10, STEP TEENS, STEP UP, etc.) investigating the effect of semaglutide 2.4mg/weekly on chronic weight management [14]
PlexusDx requires current lab work and may recommend microdose GLP-1 protocols ($129/month) or tirzepatide as safer alternatives pending nephrologist clearance