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Protein intake deserves particular attentionadequate protein (1.0-1.2 g/kg body weight daily during active weight loss) supports lean muscle mass preservation, which contributes to metabolic heat production

Verdict at a Glance Ipamorelin is the preferred choice for most research contexts due to its exceptional selectivity producing clean GH release without cortisol, prolactin, or appetite effects

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American Society of Anesthesiologists consensus-based guidance on preoperative management of patients on glucagon-like peptide-1 receptor agonists

Blinding was not implemented during the treatment phase, but all outcome assessments were conducted without prior knowledge of group assignment to minimize bias

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