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We actually prefer SQ because its painless and has an established track record of effective B12 delivery, whereas IM can be painful and tends to put people off self-injecting

Taken together, these data demonstrate that CYP-driven bioconversion of APAP occurs in our model and augments mortality, thus recapitulating similar findings described in vertebrate models 31

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doi: 10.1016/j.bcmd.2012.10.006 111 LangloisM

Self-administration is not routinely offered in the NHS unless there are exceptional circumstances and a formal arrangement is in place