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Factors affecting injection duration include the underlying cause of deficiency, pregnancy, inflammatory conditions, and medications such as metformin and proton pump inhibitors

Lyophilized powder is more stable and can be stored longer according to powder form storage protocols

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Side effect comparison All three compounds share a similar gastrointestinal side effect profile, which is expected given that all three activate the GLP-1 receptor

However, the CagriSema combination showed a higher odds ratio for diarrhea at 6.60 compared to semaglutide alone at 2.37

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