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Once outside the cell, glutathione (GSH) degradation occurs exclusively in the extracellular space, and only on the surface of cells that express the ectoenzyme -glutamyl transferase

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However, neutrophil activation levels and phagocytic capacity gradually decrease

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Studies show its essential for T-cell proliferation, natural killer cell activity, and proper inflammatory response 6

Studies have shown that when combined with antibiotics like ciprofloxacin, TB-500 significantly improves clinical outcomes by enhancing wound healing, reducing bacterial load, and modulating inflammation