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water, and a 30-minute wait) to be effective, and side effects such as nausea, vomiting, and diarrhea are still common

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Our observations suggest that prior ICI exposure may lower the threshold for immune tolerance, thereby amplifying drug-induced immune responses

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Conclusions These results demonstrate that gene-expression changes associated with regional emphysema severity within an individual's lung can provide insights into emphysema pathogenesis and identify novel therapeutic opportunities for this deadly disease

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