[11] [12] Treatment Algorithm Anti-obesity medications should be selected according to BMI, obesity-related complications, obesity stage, contraindications, patient preference, route of administration, cost, access, prior response, and long-term treatment goals
Top Research Studies on GLP-1s and Cardiovascular Outcomes The November 2023 issue of The New England Journal of Medicine shared results from a research study (SELECT) involving 17,000 patients that showed the use of semaglutide was linked to a 20% reduction in the risk of major adverse cardiovascular events such as heart disease, stroke and peripheral arterial disease in patients who had previously been diagnosed with heart disease
Targeting IGF1 to alleviate obesity through regulating energy expenditure and fat deposition
How did this happen
Health goals + history + baseline needs
Orforglipron, a non-peptide GLP-1 receptor agonist, represents another daily oral incretin-based AOM displaying dose-dependent BW and WC reductions at 36 weeks ranging from 9.4 to 14.7% and from 9.6 cm to 13.6 cm with the 12 and 45 mg dose, respectively, in mostly female (59%) patients with a mean age of 54.2 years and BMI 37.9 kg/m 2 44
