Clinical trials have not reported any serious reactions or toxicities [42]
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Clinically, heat stress patients often present with decreased platelet count and fibrinogen (FIB) levels, prolonged coagulation time, and elevated D-dimer levels
Xu DX, Chen YH, Wang H, Zhao L, Wang JP, Wei W: Effect of N-acetylcysteine on lipopolysaccharide-induced intra-uterine fetal death and intra-uterine growth retardation in mice
High levels of systemic oxidative stress that use up the active (reduced) form faster than it can be replenished
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