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The inflammatory mediators produced by microbiome dysbiosis (IFN- , TNF- , and IL-6) may increase the expression of apolipoprotein A-1 (APOL1)

Salter MW, Stevens B

The GSH effects on apoptosis and inhibition of T-cell proliferation could explain why patients with SARS-CoV-2 infection and COVID-19 disease develop lymphopenia and subsequent failure of the immune system (Khanfar and Al Qaroot, 2020)

Venkidesh et al

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In RA patients, osteoclast differentiation is regulated by the RANKL/RANK/OPG pathway