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Mean change in body weight from baseline to Week 52 was a secondary endpoint.* Comparable weight reduction with RYBELSUS 14 mg vs Jardiance PIONEER 2 study design 1,3 In an open-label trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 822 adult patients with type 2 diabetes on metformin were randomized to RYBELSUS 14 mg (n=411) or Jardiance 25 mg (n=410), both once daily

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Participants treated with all doses of oral semaglutide experienced greater reductions in FPG and 7-point SMPG than those treated with sitagliptin 100 mg

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Avoid Caffeine and Sugar Drinks Caffeine, found in coffee, energy drinks, and some teas, can inhibit your body's natural production of glutathione when consumed in excess