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The denominator (total users) isn't publicly available, which means you can't calculate a per-user risk from these figures

10.1056/NEJM199612053352301 [DOI] [PubMed] 49.POISE Study Group

The group also had close ties with anatomists and physiologists at the University of Lund with considerable expertise in endocrine cells of the gastrointestinal tract (Holst 2024)

Shantaram et al., 2025

"Originally that was thought to be mostly skeletal, we're starting to see some evidence that's smooth, and even cardiac tissue that's being lost as well." This shift is pushing researchers to look beyond the simple calories-in-calories-out equation

We recommend patients seek out and review the prescribing information and medication guides (available online) for any prescription medication to help guide an informed conversation with the prescriber