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Phase 3: optimization (weeks 11-18) Now you are in therapeutic territory
How side effects change across the dosing schedule Your ideal injection day may change as you move through the tirzepatide dose escalation schedule
Experience lasting results
This dual action results in significant caloric reduction and subsequent weight loss, with clinical trials demonstrating average weight reductions of 15-21% of body weight over 72 weeks in the SURMOUNT-1 and SURMOUNT-2 trials
While metformin does cross the placenta, multiple studies and meta-analyses have not demonstrated increased risks of major congenital malformations compared to insulin therapy
Check your tirzepatide dosing in units carefully to ensure accuracy at this level
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