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It has been shown that modification of the C-3 position can effectively enhance the antiproliferative ability of caudatin against various cancer cell lines compared to the parent compound, presumably due to improved membrane permeability facilitated by increased lipophilicity (Figure 1g) exhibited the highest activity against HepG2 cells (IC 50 3.11 M) ( To summarize, the esterification and glycosylation of C-3 OH might be beneficial for improving bioactivity and lipid solubility

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Researchers are actively conducting in vitro and laboratory studies on DSIP in lyophilized vial formats to investigate its biochemical properties in the following areas

In 97% of cases, an individuals cross-timepoint distance is lower than the median inter-individual distance