As director of the Washington Centre for Weight Management and Research, Domenica Rubino has become frustrated with growing perceptions over the last three years that weight loss drugs such as Novo Nordisk's Ozempic and Wegovy, and Eli Lilly's Mounjaro, are permanent cures for obesity
The most common side effects are gastrointestinal, like nausea, diarrhea, vomiting, or constipation
Clinical Perspective The panel concluded that the benefits of GLP-1RAs far outweigh potential ocular risks, given their proven: ~11.5 % HbA1c reduction 515 % weight loss (SURPASS & STEP programs) ~1426 % relative risk reduction in major CV events Hence, appropriate screening, not avoidance, should guide practice
Consistency optimizes pharmacokinetic profiles and establishes a routine that supports adherence
519 The activation of this pathway enhances cell proliferation and metastatic capabilities by promoting epithelial-mesenchymal transition (EMT), thereby increasing the invasiveness and metastatic potential of tumors
Next step: Ask your veterinarian for a taurine blood test at your dog's next visit, then explore a dog-specific cardiac support option if your vet recommends supplementation
