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These reductions were accompanied by significant body weight loss, confirming a robust pharmacodynamic response

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Lebwohl M, Egeberg A, Linaberry M, Hoyt K, Banerjee S, Kisa RM, Strober B (2023) Deucravacitinib in moderate to severe plaque psoriasis: liver transaminase results from the phase 3 POETYK PSO program

Interestingly, BSO significantly enhanced L-PAM-induced apoptosis in TP53 -mutated MM cell lines, suggesting that BSO+L-PAM can achieve p53-independent cell death as described previously

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