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If cumulative exposure makes you or your clinician uneasy (say you've been running cycles for over a year), shift to 12 on, 8 off

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Methylcellulose is a semi-synthetic bulk-forming laxative that adds bulk to stools without fermentation, making it may be less likely to cause gas and bloatinga potential advantage for patients already experiencing GLP-1-related gastrointestinal discomfort

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