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Common Xenobiotic Induction Pathways and Effect On Liver Morphology Induction Involving Constitutive Androstane Receptor Barbiturates and chemicals that induce CYP2B initially interact with the constitutive androstane receptor (CAR) that translocates to the nucleus and dimerizes with the retinoid-X-receptor (RXR)

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The remaining livers were put into sterilized cryopreservation tubes and quickly stored in liquid nitrogen for liver metabolomics analysis and metabolic enzyme activity determination