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10.1016/j.ceca.2016.06.009 37 FroeseD
In the 24-week study of patients receiving JANUVIA as add-on combination therapy with metformin, there were no adverse reactions reported regardless of investigator assessment of causality in 5% of patients and more commonly than in patients given placebo
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The breathlessness - its just goneWhereas before just going to the bathroom or kitchenId be puffing and panting. (P2, male, obesity)
Additionally, in another Phase II study targeting patients with T2DM, orforglipron also showed significant effects in reducing A1C and weight, achieving the studys primary and secondary endpoints
But for someone with 40, 60, or 80+ lb to lose, the difference between a 14.9% and 24.2% average outcome is enormous in practical terms and potentially transformative for metabolic health markers
