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Established Semaglutide as the reference pharmacological tool for studying GLP-1R-mediated obesity biology

Non-arteritic anterior ischemic optic neuropathy (NAION) is a condition characterized by a sudden decrease in vision due to reduced blood flow to the optic nerve

The composite heart failure endpoint (cardiovascular death or hospitalization/urgent visit for heart failure) showed a 21% reduction (hazard ratio 0.79)

This study population was then divided into two cohorts: (1) Semaglutide cohort 688 patients prescribed semaglutide, and (2) non-GLP1-RA anti-obesity medication cohort 1,346 patients prescribed non-GLP-1RA anti-obesity medications but not semaglutide

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Yang Y, et al