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Combining genetic insights with clinical history and biomarker context can support a more personalized conversation with your healthcare provider about optimizing your GLP-1 therapy

doi: 10.1186/S12864-024-10013-X 219 MillmanJRXieCVan DervortAGrtlerMPagliucaFWMeltonDA

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The progression of ALS is driven by a complex interplay among astrocyte abnormalities, chronic neuroinflammation, and TDP-43 aggregation, forming a unique web of interconnected pathologies

We observed similar behaviour in Trkb Penk -KO mice: from 810 months of age, mutants travelled significantly more than controls ( Trkb Penk -WT) (Fig