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Slow ramp-up: Doses increase gradually over several months to minimize side effects

Common side effects may include nausea, vomiting, diarrhea, constipation, abdominal pain, reduced appetite, or indigestion

One patient, Mistie Mace, lost more than 50 pounds and was able to discontinue diabetes medications through this supported, gradual approach

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In contrast to our study, theirs reported similar HbA1c and pH levels between the two groups, possibly due to different ethnicities (Middle East and North Africa), higher BMI (mean BMI 29.8 kg/m 2 ), and higher proportion of insulin users (67.4%)