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Under the policy, foreign semaglutide and tirzepatide API shipments could be detained without physical examination unless they came from manufacturers the FDA had reviewed and added to the agencys green list. The March and April 2026 data suggest that the increased FDA scrutiny is altering the behavior of illicit importers

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It enrolled 2,339 adults with obesity or overweight plus at least one weight-related comorbidity, but without diabetes

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Those with certain genetic traits might be more sensitive