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Through paracrine signaling, 123,124 endogenous EVs mediate intercellular communication and have demonstrated therapeutic potential for cardiac regeneration following acute myocardial infarction (AMI)

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Clinical Benefits: Central role in hepatic detoxification and elimination of harmful compounds Neutralises free radicals and reduces oxidative stress at a cellular level Supports and modulates immune system function Regenerates Vitamins C and E, amplifying antioxidant activity May support mitochondrial function and energy production Associated with reduced inflammation and improved cellular health Glutathione is particularly relevant for patients with chronic illness, high toxic burden, or those undergoing treatments that increase oxidative stress

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8 Gastrointestinal side effects are most common, particularly during medication initiation and with dose escalation

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