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Glucagon-like peptide 1 (GLP1) is secreted by intestinal L-cells, regulates glucose homeostasis and has inhibitory effect on gastrointestinal motility ( This study aimed to compare jejunal contractile responses to muscarinic receptor stimulation between obese patients with type 2 diabetes (OB+/DM+) and obese patients without diabetes (OB+/DM), and to assess the effects of GLP-1 and GIP on jejunal contraction in relation to jejunal muscle expression of these peptides, their receptors, and DPP-4

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Titrating this medication helps to reduce gastrointestinal side effects mentioned in the side effects section of the above tutorial video

Apparently, just five percent of Americans eat enough fiber per day