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V.ZehtabO.GuigoR.et al (2003)

10.1186/s12987-019-0145-6 Fluids Barriers CNS 32 CarabottiM.SciroccoA.MaselliM

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According to the NCCD, the key determinants that define apoptosis as an RCD are its initiation by caspase-8 and caspase-9 and cell death execution by caspase-3, caspase-6, and caspase-7, which occur at the terminal stage when the cells are already committed to die [6, 73]