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The second hexa-histadine tag of the protein was not utilized in these experiments, but is relevant and must be noted because Ni-NTA was used to purify the GST-GFP for several of the experiments being discussed

Table 1 the preparation used in the present invention is able to deliver therapeutically active amounts of glutathione to the system in spite of these concerns

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This transformation enhances mucosal adhesion, prolongs drug retention, and facilitates sustained drug release, ultimately improving bioavailability and therapeutic efficacy (Illum, 2000)

Overall, addressing GPx levels offers hope for slowing these disorders