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Because B12 is water-soluble, excess amounts are safely excreted by the body

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10.1016/j.intimp.2023.110593 115 MarkoulliM.AhmadS.ArcotJ.AritaR.Benitez-Del-CastilloJ.CafferyB.et al (2023)

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PMID 23356638

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A researcher prioritising sustained exposure over 6 hours would choose SubQ despite slightly lower total bioavailability

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