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The resident immune cells of the CNS, microglia, are key players in homeostatic maintenance, response to injury, and mediating neuroinflammatory processes

Despite discontinuation, bisphosphonates anti-fracture effects persist because this medication class has long half-lives and remain stored in bone for up to 10 years

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Key highlights Tirzepatide is a once-weekly injectable medication that acts as a dual agonist of GLP-1 & GIP receptors, while orforglipron is a daily oral GLP-1 receptor agonist