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This approval applies to Europe, the USA, Canada, and the UK (4143)

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Results of experimental and clinical investigations demonstrated the effects of the synthetic peptide on the course of retinitis pigmentosa, a degenerative process of the retina resulting from disturbed metabolism of specific proteins in the pigmented epithelium and other retinal layers [38]

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Specific disulfide linkage between homocysteine and the sulfhydryl group of an intracellular protein may be an alternative molecular mechanism underlying hyperhomocysteinemia-induced vascular dysfunction

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