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The percentage-point change in total fat mass, lean mass, and visceral fat mass proportions, measured by dual energy X-ray absorptiometry (DXA), was 3.5%, 3.0%, and 2.0%, respectively, with semaglutide compared to 0.2%, 0.1%, and 0.01% with placebo [20] (Table 1)

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But the differences between these two approaches run deep, from the molecular level all the way through to real-world results, side effect profiles, administration routes, and long-term safety data

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194 of those patients were taking semaglutide versus 516 who were on non-GLP-1 RA medications