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These occur as the heart works harder to compensate for lower oxygen levels in the blood, a response that can be more pronounced in older adults

[DOI] [PubMed] [Google Scholar] 131.Cesar L.B., Gojkovic S., Krezic I., Malekinusic D., Zizek H., Vuletic L.B., Petrovic A., Pavlov K.H., Drmic D., Kokot A., et al

Chronic tissue has adapted to a damaged state, and reversing this takes time